Geroscience: EZZ brand NMN can delay aging

February 27 03:43 2020

With aging, our overall gene expression will gradually change, thus making our immune system more prone to generate chronic inflammation, cells more prone to show apoptosis, mitochondria more prone to produce oxidative stress. These changes appear in different parts of our bodies, causing different problems.

In 2019, a team of U.S. scientists found that NMN significantly restored neurovascular status and cognitive function in aged mice. The study was published in Geroscience, a journal of aging research, on February 13, 2020.

The researchers first gave aged mice a NMN intraperitoneal injection (500mg / kg) for two weeks. Subsequently, it was found that the expression of 590 genes related to nerve and blood vessels in the aged mice injected with NMN had changed compared with the ordinary aged mice by transcriptome sequencing. Among them, the expression of 204 genes recovered to that in the young mice. The researchers concluded that the anti-aging ability of NMN was achieved by the longevity gene SIRT1 activated by NAD +.

First of all, SIRT1 could restore mitochondrial function. As the main place of aerobic respiration, mitochondrial function decline is a main line of aging phenomenon. NMN could significantly restore mitochondrial function. Secondly, SIRT1 could resist inflammation, prevent vascular aging and enhance immunity. Study showed that chronic inflammation characterized by endothelial cell activation was one of the signs of all vascular aging, and SIRT1 could significantly inhibit inflammation, maintain vascular activity, and enhance human immunity.

The researchers concluded that with aging, o our overall gene expression will gradually change, thus making our immune system more prone to generate chronic inflammation, cells more prone to show apoptosis, mitochondria more prone to produce oxidative stress. These changes appear in different parts of our bodies, causing different problems. By supplementing NMN, this problem can be solved fundamentally.

The reporter has learned that currently, the industrialization of NMN is one of the biggest hot spots in the current life science circle. Experts believed that safety is the biggest consideration when choosing NMN products. If consumers don’t have the ability to identify themselves, they can choose those products that have obtained the certification of the major drug administrations around the world.

Such products are more secure to purchase because of the professional audit and detection from the drug administration. Among them, EZZ brand NMN developed by New Zealand gene research center, the top gene research institution in the world, has obtained TGA certification in Australia. Compared with the certification standards of many NMN products, such as FDA certification, TGA certification is recognized as the most stringent FDA certification in the world, with higher value.

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